Adsorption and Electrooxidation of Nucleic Acids at Glassy Carbon Electrodes Modified with Multiwalled Carbon Nanotubes Dispersed In Polylysine

YAMILE JALIT; MÓNICA MORENO; FABIANA A. GUTIERREZ; ALBERTO SÁNCHEZ ARRIBAS; MANUEL CHICHARRO; ESPERANZA BERMEJO; ANTONIO ZAPARDIEL; CONCEPCIÓN PARRADO; GUSTAVO A. RIVAS; MARCELA C. RODRIGUEZ

WILEY-V C H VERLAG GMBH

Lugar: Weinheim; Año: 2013 p. 1116 - 1116

font size="1" face="AdvTTR"> We report the advantages of the adsorption and electrooxidation of oligonucleotides and calf-thymus double stranded DNA (dsDNA) at glassy carbon electrodes (GCE) modified with a dispersion of multiwalled carbon nanotubes (MWCNT) in poly-l-lysine (Plys) (GCE/MWCNT-Plys). Important enhancement in the guanine oxidation signal was obtained by adsorptive stripping voltammetry (AdSV) due to a most favorable interaction between the negatively charged DNAs and the positively charged Plys that support the MWCNT. The layer of oligo(dG)11 immobilized at GCE/MWCNT-Pl